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Folaţii sunt compuşi ai acidului pteroilglutamic, care funcţionează ca şi coenzime în reacţii metabolice care implică transferul unei unităţi de carbon. Folaţii şi vitamina B12 sunt esenţiali。

Diagnosticul de laborator al deficitului de acid folic include măsurarea de folați serici și folat eritrocitar. În sânge, 95% din acidul folic este în eritrocite. Prin urmare, acidul folic determinat。

Ortiz Z, et al. Folic acid and folinic acid for reducing side effects in patients receiving methotrexate for rheumatoid arthritis (review). Theacid folic bioclinica Cochrane Collaboration. Published by JohnWiley & Sons, Ltd. 2009.

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